骨质疏松症的负担和治疗:一个系统的文献综述
Molly C Murton1, Emma L A Drane2, Danielle M Goff-Leggett2
1Costello Medical Consulting Ltd, London, UK.
Advances in therapy
|June 29, 2023
概括
骨髓质疏松症显著影响生活质量和医疗保健成本. 虽然像沃索里提德 (vosoritide) 这样的治疗方法显示出希望,但需要对长期影响和成本效益进行更多研究.
科学领域:
- 医学研究 医学研究
- 遗传学 遗传学 是一个
- 公共卫生 公共卫生
背景情况:
- 骨发育不良是一种常见的骨发育不良,需要了解其健康负担和治疗选择.
- 最近的治疗进展凸显了对形细胞增生症影响的全面数据的需求.
结论:
- 这本SLR提供了阿德罗普拉西亚的负担和治疗景观的全面概述.
- 鉴定到的证据缺陷包括缺乏对形质疏松症及其新兴疗法的实用性和成本效益数据.
- 该审查强调,随着新的治疗证据的出现,需要持续更新.
更多相关视频
09:51The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
Published on: September 7, 2022
2.7K
14:49Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Published on: September 29, 2018
42.0K
相关概念视频
02:41Lethal Alleles
15.6K
Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
15.6K
01:09Changes in the Appendicular Skeleton with Age
2.1K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
2.1K
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
17
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
17