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Updated: Jul 25, 2025

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在BUD13体质功能增益突变通过破坏Fbw7功能来促进瘤发生

Jianfeng Chen1,2, Xinyi Zhang1, Xianming Tan1,3

  • 1Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill , Chapel Hill, NC, USA.

The Journal of experimental medicine
|June 29, 2023
PubMed
概括

癌症通过体质突变劫持酶识别动机,如BUD13变体,以促进结肠癌的生长. 针对这些突变提供了新的治疗策略,并有助于患者分层.

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