骨密度降低及其相关因素在脏移植接受者:一个横截面研究
B Gheiasi1, M Hadavi1, R Asadzadeh1
1Department of Internal Medicine, School of Medicine, Shahid Mostafa Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran.
International journal of organ transplantation medicine
|June 29, 2023
概括
接受脏移植的人经常经历骨矿物质密度 (BMD) 的下降. 普雷德尼索隆的使用,年龄和维生素D水平是影响这些患者骨质疏松风险的关键因素.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 整形外科 整形外科 整形外科
背景情况:
- 骨矿物质密度 (BMD) 降低是移植后的常见并发症.
- 有助于减少BMD的因素众多,但研究结果仍然不一致.
研究的目的:
- 为了确定移植接受者减少骨硬度的患病率.
- 为了确定与该患者群体的BMD减少相关的因素.
主要方法:
- 一项研究包括在2016-2018年期间接受脏移植的69名接受者.
- 骨矿物质密度 (BMD) 用双能X射线吸收计进行评估.
- 统计分析包括后勤回归来确定风险因素.
主要成果:
- 整体骨质疏松症的发病率在股骨中为38%,在腰椎中为32%.
- 在年轻患者 (<50岁) 中,骨质疏松症与维生素D水平和性别有关.
- 在老年患者 (>50岁) 中,骨质疏松症的风险随着年龄和使用普得尼索隆的持续时间而增加.
结论:
- 普雷迪尼索隆的消费是移植后骨质量减少的一个重要因素.
- 定期的BMD监测和最大限度地减少普雷尼索隆剂量对于预防至关重要.
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