在巴基斯坦绘制家族性高胆固醇血症和脂质失调的基本管理基础设施:一个横截面研究
Fouzia Sadiq1, Saeed Shafi2, Jaka Sikonja3,4
1Shifa Tameer-e-Millat University, Islamabad, Pakistan.
The Lancet regional health. Southeast Asia
|June 29, 2023
概括
巴基斯坦的家族性高胆固醇血症 (FH) 诊断不足,原因是基础设施不佳和缺乏认识. 对测试和查计划的有限访问妨碍了有效的FH管理和心血管疾病预防.
科学领域:
- 心脏病学 心脏病学
- 遗传学 是一个遗传学.
- 公共卫生 公共卫生
背景情况:
- 家族性高胆固醇血症 (FH) 是一种遗传性疾病,导致高LDL胆固醇和早期心脏病.
- 尽管FH对公共卫生的重要性很大,但在全球范围内,尤其是低收入国家,由于意识和基础设施有限,FH的诊断严重不足.
研究的目的:
- 评估目前在巴基斯坦管理家族高胆固醇血症的基础设施.
- 在巴基斯坦医疗保健系统中识别FH诊断和管理的障碍.
主要方法:
- 在巴基斯坦各地的128名医生 (心脏病学家,儿科医生,内分泌学家,内科专家) 中进行了一项调查.
- 医生报告了FH患者数量,诊断工具,查实践和治疗方法.
主要成果:
- 医生报告诊断的FH病例数量较少,获得免费胆固醇和遗传检测的机会有限.
- 级联查很少进行,没有统一的诊断标准.
- 缺乏财务资源被认为是FH管理的一个主要障碍.
结论:
- 巴基斯坦缺乏国家FH查计划,导致广泛的诊断不足和心血管风险升高.
- 有效的FH管理需要提高临床医生的意识,强大的基础设施,以及足够的资金来进行查和治疗.
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