通过针对柬埔寨艾滋病毒感染者的交互式定制消息来终止烟草使用 (EndIT项目):随机对照试验的协议
Thanh Cong Bui1,2, Charles E Hoogland3, Chhorvann Chhea4
1Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.
JMIR research protocols
|June 29, 2023
概括
这项研究测试了柬埔寨艾滋病毒感染者的移动健康戒烟计划. 自动化消息干预显示了改善戒烟率和公共健康的前景.
科学领域:
- 公共卫生 公共卫生
- 数字健康干预措施 数字健康干预措施
- 艾滋病毒/艾滋病研究研究
背景情况:
- 柬埔寨的吸烟率很高,特别是在艾滋病毒感染者中.
- 对于这一群体,迫切需要具有成本效益的戒烟干预措施.
- 这项研究评估了基于理论的移动健康 (mHealth) 干预.
研究的目的:
- 为了比较基于移动健康的自动化消息 (AM) 干预与戒烟的标准护理 (SC) 的有效性.
- 评估AM在促进柬埔寨艾滋病毒感染者戒烟方面的有效性.
- 评估辅助干预的成本效益.
主要方法:
- 一个2组随机对照试验,有800名参与者 (吸烟的艾滋病毒感染者).
- 干预组接受AM加标准护理;对照组接受标准护理.
- 主要结局:12个月后生化证实戒烟;次要结局:3个月和6个月戒烟.
主要成果:
- 参与者招聘于2023年1月开始.
- 数据收集计划在2025年底前完成.
- 相关机构和道德审查委员会批准的研究.
结论:
- 在柬埔寨的艾滋病毒感染者中,AM干预有潜力显著提高戒烟率.
- 这种移动健康方法可能适用于其他人口和LMIC,改善全球公共卫生.
- 证明AM的有效性和成本效益可以改变艾滋病毒治疗,减少与烟草有关的疾病.
关键词:
柬埔寨 柬埔寨 柬埔寨 柬埔寨 柬埔寨艾滋病毒/艾滋病病毒/艾滋病病毒基于阶段的模型.有关RCT的RCT是什么经济效益性 经济效益性低收入和中等收入国家.移动健康 移动健康 移动健康 移动健康随机对照试验是随机对照试验.戒烟的方法 戒烟的方法更多相关视频
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
2.3K
06:28E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
8.4K
相关概念视频
Study Designs in Epidemiology
280
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
280
Hazard Ratio
165
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
For example, in a clinical trial...
165
Clinical Trials: Overview
3.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.0K
Community Based Intervention
66
Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
66
Blinding
2.5K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.5K
Randomized Experiments
7.0K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
7.0K
