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机械血栓预防在巴西剖腹产的成本效益
Alex Veloz1, Ubong Silas2, Rhodri Saunders2
1Health Economics and Clinical Outcomes Research, Xavier University, Cinncinati, Ohio, United States of America.
PloS one
|June 29, 2023
概括
间歇性气动压缩是预防巴西剖腹产患者静脉血栓栓塞的经济有效方法. 这种机械预防比低分子量肝素更合适,更具成本效益.
科学领域:
- 产科和妇科 产科和妇科
- 卫生经济学 卫生经济学
- 血管外科 血管外科
背景情况:
- 静脉血栓塞栓症 (VTE) 是接受剖腹产的患者的一个重大风险.
- 有效和成本效益的预防策略对于改善患者的治疗结果和管理医疗保健成本至关重要.
研究的目的:
- 评估机械血栓预防的成本效益,特别是间歇性气压压缩 (IPC),与低分子量肝素 (LMWH) 相比,在巴西的剖腹产患者没有预防.
主要方法:
- 开发了一个决策分析模型来比较IPC,LMWH和没有预防的成本和有效性.
- 数据来源于同行评审的文献,考虑了诸如VTE,轻微出血和重大出血等不良事件.
- 进行了灵敏度分析,以评估不确定性对模型结果的影响.
主要成果:
- 发现IPC与没有预防相比具有成本效益,每次避免不良事件的增量成本效益比为R$7,843.
- IPC主导着LMWH,提供更低的成本和更高的效率.
- 概率敏感性分析表明,IPC和无预防药物具有相似的成本效益概率,而LMWH不太可能具有成本效益.
结论:
- 间歇性气动压缩是一种具有成本效益的,并且可能比LMWH更适合的预防方案,用于巴西剖腹产患者的静脉瘤预防.
- 血栓预防的决定应该是个性化的,并基于风险分层.
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