在实时功能性MRI情绪自我调节训练后改变了杏仁体的功能连接性
Hui Gao1, Huan Zhang2, Linyuan Wang1
1Henan Key Laboratory of Imaging and Intelligent Processing, PLA Strategic Support Force Information Engineering University, Zhengzhou.
Neuroreport
|June 29, 2023
概括
实时功能性MRI神经反 (rtfMRI-NF) 通过训练对杏仁体活动的自愿控制来增强情绪调节. 这种技术显示出治疗情绪相关精神障碍的潜力.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 医疗成像医学成像
背景情况:
- 实时功能性MRI神经反 (rtfMRI-NF) 是一种用于监测和调节大脑活动的非侵入性方法.
- 杏仁体在情绪处理和调节中起着至关重要的作用.
- 了解功能连接变化是阐明神经反机制的关键.
研究的目的:
- 调查rtfMRI-NF对基于杏仁体的情绪自我调节的影响.
- 分析神经反训练后休息状态功能连接的变化.
- 探索情绪调节改善背后的神经机制.
主要方法:
- 一个基于任务的实验,使用rtfMRI-NF来训练情绪自我调节.
- 参与者被分成两组,对杏仁体活动进行上调或下调.
- 休息状态功能连接在神经反之前和之后使用对对样本t测试进行了评估.
主要成果:
- rtfMRI-NF训练显著增强了对大脑反应的自愿控制.
- 默认模式网络和边缘系统区域之间的功能连接性存在显著差异.
- 上调组显示左半球活动增加,可能与积极情绪有关.
结论:
- rtfMRI-NF有效地提高了个体调节情绪反应的能力.
- 在训练后发现了杏仁体功能连接电路的明显变化.
- 研究结果表明,rtfMRI-NF在治疗情绪障碍方面具有潜在的临床应用.
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