相关实验视频

Updated: Jul 25, 2025

Prehospital Thrombolysis: A Manual from Berlin

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

在复发性缺血性中风中超早期重复系统性血栓溶解 - 一个多中心病例研究

Thorleif Etgen¹, Manuel Cappellari², David Černík³

¹Klinik für Neurologie, Klinikum Traunstein, Germany; Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technische Universität München, Germany.

Journal of the neurological sciences

|June 29, 2023

概括

对于缺血性中风复发的超早期重复血栓溶解 (UERT) 显示了早期临床改善和良好的结果的高率. 脑内出血率与现有数据相当,这表明UERT可能是一个可行的选择.

科学领域:

神经学神经学
血管神经学血管神经学
紧急医疗紧急医疗

背景情况:

缺血性中风在10天内复发是一个关键的临床挑战.
非标签重复血栓溶解是超早期中风复发的新兴策略.
重组组织等离子体激活剂 (rt-PA) 是一个关键的血栓解压剂.

研究的目的:

分析接受非标签超早期重复血栓溶解 (UERT) 治疗的患者因缺血性中风复发的结果.
在现实环境中评估UERT的有效性和安全性.
评估UERT后的早期临床改善率和良好的结果.

主要方法:

追溯的多中心案例研究.
从TEMPiS注册和数据库搜索中识别患者 (PubMed,谷歌学者).
对人口统计,临床,实验室和成像数据的分析,详情请作者联系.

主要成果:

16名患者接受了UERT,治疗之间的中位时间为3.5天.
85.7%的患者表现出早期临床改善 (NIHSS减少≥4).
68.8%的人取得了良好的结果 (3个月的mRS 0-2);25.0%的人经历了脑内出血 (ICH),其中有一个致命事件.

结论:

在早期复发性缺血性中风患者中,UERT显示显著的早期临床改善和有利的结果.
ICH利率与现有出版物相当,这表明一个可管理的风险概况.
在经过谨慎的风险效益评估后,可以考虑在某些早期复发性中风患者中进行UERT.

关键词:

急性缺血性中风是一次急性缺血性中风.脑内出血脑内出血多中心案例研究.经常发生的缺血性中风.重复发生的血栓溶解.

更多相关视频

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model

Published on: June 4, 2021

相关概念视频

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...