抗生素检测的新方法:使用方波电压计
Júlia Duarte Megale1, Djenaine De Souza1
1Laboratory of Electroanalytical Applied to Biotechnology and Food Engineering (LEABE), Chemistry Institute, Uberlândia Federal University, Major Jerônimo street, 566, Patos de Minas, MG 38700-002, Brazil.
Journal of pharmaceutical and biomedical analysis
|June 29, 2023
概括
环境中的抗生素残留物对生态系统和农业构成风险. 方波电压测量为检测水和生物流体等各种样本中的这些新出现的污染物提供了一种敏感的方法.
科学领域:
- 分析化学 分析化学
- 环境科学 环境科学
- 制药科学 制药科学
背景情况:
- 抗生素对于治疗细菌感染至关重要,但它们的释放给环境带来了重大的生态和公共卫生风险.
- 抗生素残留物是新出现的污染物,可能会破坏陆地生态系统和畜牧业和水产养殖等农业部门.
- 有效的分析方法对于检测各种环境和生物矩阵中的低度抗生素至关重要.
研究的目的:
- 审查方形波电压测量 (SWV) 的应用,以分析确定抗生素.
- 涵盖各种化学类抗生素和各种样本类型和电压传感器中使用的工作电极.
- 评估SWV在检测复杂基因表中抗生素的实用性,包括环境和生物样本.
主要方法:
- 从Science Direct和Scopus数据库中对科学出版物的系统文献审查.
- 分析了2012年1月至2023年5月期间发表的研究,重点关注用于抗生素检测的SWV.
- 检查各种工作电极和样品类型,用于抗生素的电压测量.
主要成果:
- 方波电压测量证明了各种抗生素定量分析的广泛适用性.
- SWV已成功应用于检测尿液,血液,天然水和牛奶等复杂基质中的抗生素.
- 经过审查的文献强调了SWV作为抗生素残留物确定敏感技术的有效性.
结论:
- 方波电压测量是一种多功能且有效的分析技术,用于在各种环境和生物样本中检测抗生素.
- 持续开发和应用SWV传感器对于监测抗生素污染和减轻相关风险至关重要.
- 本次审查强调了SWV在应对新出现的抗生素污染物所带来的挑战方面的重要性.
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