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Updated: Jul 25, 2025

Chromosome Preparation From Cultured Cells
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在初级瘤中丧失Y染色体

Meifang Qi1, Jiali Pang2, Irene Mitsiades3

  • 1Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129, USA; Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Cell
|June 29, 2023
PubMed
概括

在老年男性中,Y (LOY) 染色体的丢失很常见,并且与疾病有关. 这项研究对5000多个男性瘤的LOY进行了分类, 揭示了其多种作用和潜在的治疗脆弱性.

关键词:
Y染色体癌症基因组学性染色体身体拷贝数的变化皮膜黑色素瘤

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