计算机断层扫描衍生的身体组成,全身炎症和腹腔大动脉动脉瘤患者的生存率之间的关系
Nicholas A Bradley1, Amy Walter2, Alasdair Wilson3
1Academic Unit of Surgery, University of Glasgow, Glasgow, UK.
Journal of vascular surgery
|June 29, 2023
概括
结合计算机断层扫描 (CT) 衍生体质分析 (CT-BC) 和全身炎症等级 (SIG),可改善接受腹腔大动脉瘤 (AAA) 修复的患者的风险预测. 这种方法提高了选择性AAA干预的生存预测.
科学领域:
- 血管外科 血管外科
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 对于腹腔大动脉瘤 (AAA) 修复的患者选择仍然具有挑战性.
- 计算机断层扫描 (CT) 衍生体质分析 (CT-BC) 和系统性炎症等级 (SIG) 在AAA内血管修复中显示出预后价值.
- 在接受AAA干预的非癌症人群中,CT-BC和SIG的数据有限.
研究的目的:
- 研究CT-BC,SIG和接受选择性AAA干预的患者的存活率之间的关系.
- 评估结合CT-BC和SIG对AAA修复结果的预后价值.
主要方法:
- 对611名在三个高等医疗中心接受选择性AAA干预的患者的回顾性分析.
- CT-BC分析包括CT衍生的肉症评分 (CT-SS),皮下和内脏脂肪指数.
- 从手术前的血液测试中计算SIG;结果是整体和5年死亡率.
主要成果:
- 升高的CT-SS和SIG独立地与增加的死亡风险相关 (分别P <.001和P <.01).
- 低CT-SS和SIG患者的生存时间 (92.6个月) 与高得分 (44.9个月) 患者相比显著更长.
- 低风险患者的五年生存率为90%,高风险患者为34% (P < .001).
结论:
- 结合CT衍生和全身炎症评分,为选择性AAA干预提供了预后价值.
- 这种综合方法可能会增强AAA患者未来的临床风险预测策略.
更多相关视频
06:46Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection
Published on: July 16, 2018
9.6K
06:56Author Spotlight: The Significance of Isolation, Culture, and Adipogenic Induction of SVF-Derived Preadipocytes from Mouse Perivascular Adipose Tissue
Published on: July 21, 2023
2.3K
相关概念视频
Aneurysm II: Clinical Manifestations and Diagnostic Studies
10
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
10
Aneurysm III: Interprofessional Care
10
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
10
Coronary Artery Disease I: Introduction
25
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
25
