一般医生的怀孕意识:趋势和与危险药物使用的关联
Eline Houben1, Karin Ma Swart2, Eric Ap Steegers3
1PHARMO Institute for Drug Outcomes Research, Utrecht; Department of Obstetrics and Gynaecology, Erasmus MC, Rotterdam.
概括
在处方危险药物时,全科医生对怀孕的认识较低. 尽管情况有所改善,但未经确认怀孕的女性更有可能接受危险药物,这凸显了需要更好的处方做法.
科学领域:
- 药物监督 药物监督 药物监督
- 生殖健康 生殖健康
- 一般的做法一般的做法
背景情况:
- 一般医生 (GPs) 是提供产前护理的关键.
- 有限的数据存在于GP意识到怀孕在药物处方期间.
研究的目的:
- 在处方具有潜在安全风险的药物时,评估GP对怀孕的认识.
- 确定GP怀孕意识和处方危险药物之间的关联.
主要方法:
- 基于人口的研究,使用链接的全科医生和确认的怀孕记录 (2004-2020年).
- 通过GP系统的确认评估GP怀孕意识.
- 分析了使用多变量逻辑回归的原药物处方.
主要成果:
- 在48%的怀孕中,GP怀孕确认存在,从2004年的28%上升到2020年的63%.
- 在3%的孕妇处方高危药物,只有13%的初始处方得到确认.
- 没有确诊怀孕的女性接受危险药物的可能性增加了59% (OR 1.59).
结论:
- 在处方危险药物时,GP对怀孕的认识仍然是一个问题.
- 虽然怀孕登记有所改善,但药物安全信息系统的最佳使用缺乏.
- 需要加强系统和实践,以提高孕妇的药物安全性.
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