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一个微随机的试点研究,以检查恰到好处的冲动对2型糖尿病成年人的晚餐后零食的影响:一项研究协议
Lijun Zhao1,2, Niranjan Bidargaddi3, Andrew Vakulin4
1Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, Australia.
数字可以帮助减少2型糖尿病 (T2D) 患者的晚餐后零食. 这项研究使用持续葡萄糖监测 (CGM) 客观测量葡萄糖水平和零食事件.
科学领域:
- 糖尿病管理 糖尿病管理
- 行为科学 行为科学
- 数字健康干预措施 数字健康干预措施
背景情况:
- 晚餐后的零食在2型糖尿病 (T2D) 中很常见,并可能对血糖控制产生负面影响.
- 对零食及其对葡萄糖水平的影响的客观测量对于有效的T2D管理至关重要.
研究的目的:
- 为了确定晚餐后提供的数字是否会减少T2D患者的零食事件.
- 客观地测量这些推动对24小时葡萄糖水平的影响,使用持续葡萄糖监测 (CGM).
主要方法:
- 一个单位微型随机试验 (MRT) 涉及18-75岁的T2D患者.
- 参与者在4周的时间内通过CGM,睡眠传感器和餐饮摄影进行监测 (2周的预测,2周的MRT).
- 每天的微随机化分配参与者在晚餐后接受数字推动或没有推动.
主要成果:
- 主要结果是CGM曲线下的增量面积的差异,从晚餐后90分钟到凌晨4点.
- 二次结果包括葡萄糖峰值,时间范围,即时通讯的可行性,以及推动的可接受性.
- 睡眠质量的探索性分析及其与零食和血糖变化的关系.
结论:
- 这项研究提供了初步证据,证明了数字推动在改变T2D患者晚餐后吃零食行为的有效性.
- 研究结果将为未来研究的设计提供信息,通过数字干预来改善健康行为和结果.
- 一个探索性睡眠子研究将调查零食,血糖和睡眠之间的双向关系.
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