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Updated: Jul 25, 2025

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双性FBXW7淘汰诱导AKAP8介导的DNA损伤邻近的野生型细胞

Dedrick Kok Hong Chan1,2, Amit Mandal1, Svenja Hester3

  • 1Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.

Cell death discovery
|June 29, 2023
PubMed
概括

结直肠癌细胞中的FBXW7突变会通过分泌的AKAP8在邻近细胞中引起DNA损伤. 这突显了亚克隆相互作用对瘤发展的影响.

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