瑞典双胞胎中患有背部,部或肩部疼痛和常见精神障碍的病缺过渡,采用多状态方法
Sanna Kärkkäinen1,2, Jakob Bergström1, Annina Ropponen1,3
1Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Scientific reports
|June 29, 2023
概括
背部,部或肩部疼痛和常见精神障碍 (CMD) 的人面临更高的病缺和残疾风险. 家庭因素也会影响这些过渡,特别是在最初的病假期间.
科学领域:
- 流行病学 流行病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 肌肉骨疼痛和常见的精神障碍 (CMD) 是导致劳动残疾的重要原因.
- 对于公共卫生干预来说,了解进入和退出病缺和残疾养老金的过渡至关重要.
- 家庭影响,包括遗传和共同的环境因素,可能会在工作缺勤中发挥作用.
研究的目的:
- 调查过渡到和从疾病缺席和残疾养老金.
- 检查家庭影响对这些过渡的作用.
- 为了比较与疼痛,CMD和它们的同时发生相关的风险.
主要方法:
- 使用了一个瑞典双胞胎队列 (N=41,516) 出生于1935-1985.
- 通过使用国家登记册,平均在8.7年内跟踪参与者的病假.
- 采用多态考克斯回归法,并分析了受曝光异调的双胞胎对,分层按zygosity进行分层.
主要成果:
- 疼痛和CMD都增加了因病缺席和残疾养老金的风险.
- 患有疼痛和心血管疾病的个人在过渡到病假 (1.61) 和残疾养老金 (1.43) 的危险比率最高.
- 在某些过渡过程中,双胞胎与单胞胎双胞胎相比,双胞胎的危险比率更高表明了家族混.
结论:
- 背部,部或肩部疼痛和/或肌痛性肌痛疾病与明显更高的疾病缺席和重复发作的风险有关.
- 家庭因素有助于疾病缺席的风险,特别是在最初的发作.
- 联合疼痛和CMD构成长期劳动残疾的最大风险.
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