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Updated: Jun 8, 2026

Detection of Post-translational Modifications on Native Intact Nucleosomes by ELISA
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Detection of Post-translational Modifications on Native Intact Nucleosomes by ELISA

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检测酸化后翻译性修饰沿单个与纳米孔的单个

Ian C Nova1, Justas Ritmejeris1, Henry Brinkerhoff1,2

  • 1Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, the Netherlands.

Nature biotechnology
|June 29, 2023
PubMed
概括

我们开发了一种纳米孔方法来检测单个蛋白质化位点,以95%的准确度区分距离近的酸盐. 这为癌症研究的单分子分析带来了进步.

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相关概念视频

Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...