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患有COVID-19的患者心脏并发症:系统性审查
E Brogi1, F Marino2,3, P Bertini4
1Department of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, Via Paradisa 2, 56124, Pisa, Italy. etruscabrogi@gmail.com.
Journal of anesthesia, analgesia and critical care
|June 29, 2023
概括
COVID-19患者经常经历心脏并发症,急性心脏损伤是最常见的. 这种损伤是这些患者严重疾病和死亡率的重要预测因素.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 心脏并发症显著影响COVID-19患者的治疗结果.
- 了解这些并发症及其预测因素对于患者管理至关重要.
研究的目的:
- 系统地审查和描述COVID-19患者的心脏并发症.
- 确定心血管事件的预测因素,并分析心脏并发症对结果的影响.
主要方法:
- 系统审查遵循PRISMA指南,使用多个数据库.
- 对7项研究 (2115名患者) 的元分析,以计算风险比率 (RR) 和评估异质性 (I2统计).
主要成果:
- 急性心脏损伤是最常见的并发症 (20-45%),与年龄较大,并发症和死亡率较高有关.
- 急性心脏损伤独立预测严重的SARS-CoV-2感染和死亡率 (RR 0.20).
- 高血压 (30-59.8%) 和心血管疾病 (高达57%) 是常见的并发症,与严重疾病和更高的死亡率有关.
结论:
- 急性心脏损伤是COVID-19的一个关键并发症,预测了更糟糕的结果.
- 虽然心律不整很常见,但其他特定并发症 (如心肌炎) 的证据仍然有限.
- 以前存在的心血管疾病和高血压增加了严重COVID-19和死亡的风险.
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