抗微生物管理原则在重症监护室的逻辑和临床应用:一个多学科的声明
Andrea Cortegiani1,2, Massimo Antonelli3,4, Marco Falcone5
1Department of Surgical, Oncological and Oral Science, University of Palermo, Via Liborio Giuffrè 5, 90127, Palermo, Italy. andrea.cortegiani@unipa.it.
Journal of anesthesia, analgesia and critical care
|June 29, 2023
概括
在重症监护室 (ICU) 的抗微生物耐药性需要量身定制的抗微生物管理. 这份共识文件提供了优化重症患者治疗的关键陈述.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 在重症监护室 (ICU) 的抗菌素耐药性 (AMR) 导致高发病率,死亡率和医疗费用.
- 不充分的抗微生物治疗有助于多药耐药细菌的出现.
- 抗菌管理计划 (ASP) 对于改善ICU中的抗菌疗法至关重要,但需要具体的调整.
研究的目的:
- 讨论和建立关于专门针对ICU环境的抗微生物药物管理原则的共识声明.
- 为在重症患者中有效临床应用抗微生物管理提供指导.
主要方法:
- 使用了修改后的名义小组讨论方法.
- 一个多学科的专家小组召开讨论和制定声明.
主要成果:
- 主要声明强调为重症患者量身定制的抗菌药物管理.
- 建议包括准向治疗,快速诊断,个性化治疗持续时间和微生物监测.
- 强调了药理动力学/药理动力学 (PK/PD) 目标和特定的ASP指标的使用.
结论:
- 在ICU中有效的抗菌药物管理需要对一般原则进行具体的调整.
- 在重症患者中优化抗菌药物治疗需要采取多方面的方法.
- 实施这些声明可以改善结果,并打击ICU中的抗菌素耐药性.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
Standard Precaution
2.0K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
2.0K
Acute Coronary Syndrome IV: Interprofessional Care
12
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
12
Hand hygiene
3.4K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.4K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
15
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
15
Transmission-based Precautions II: Airborne and Protective Environment
1.3K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.3K


