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从PC-SAFT中纯预测活动系数可以帮助药物-聚合物兼容性查吗?

Jáchym Pavliš1, Alex Mathers1, Michal Fulem1

  • 1Department of Physical Chemistry, Faculty of Chemical Engineering, University of Chemistry and Technology, Prague, Technická 5, 166 28 Prague 6, Czech Republic.

Molecular pharmaceutics
|June 30, 2023
PubMed
概括

使用PC-SAFT探索预测无形固体分散 (ASD) 的药物聚合物兼容性. 虽然定量预测显示出重大错误,但该模型为药物配方的聚合物载体提供了有用的定性排名.

关键词:
在PC-SAFT中使用.无形固体分散的分散.兼容性兼容性兼容性的兼容性药物 药物 药物 药物 药物 药物聚合物是一种聚合物.预测 预测 预测 预测溶解度 溶解度 溶解度 溶解度

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