在低流量状态的患者中,为脊椎底座功能不充分的支架的血液动力学结果
Timothy G White1, Richard Bram2, Justin Turpin1
1Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Manhasset, NY, USA.
概括
血管整形和支架改善了有症状的动脉样硬化病患者的脊椎底流. 这种干预可以改变低流量状态的自然历史,降低中风风险.
科学领域:
- 神经内血管外科手术是一种神经内血管手术.
- 脑血管疾病管理
- 干预性神经放射学 干预性神经放射学
背景情况:
- 脊椎骨干 (VB) 系统的低流量增加了中风风险,正如VERiTAS研究所显示的那样.
- 血管内膜血管塑造和支架是耐火性疾病的症状患者的选择.
- 这些干预措施在高风险的VB低流患者的结果没有得到充分的记录.
研究的目的:
- 评估血管造形术和支架在症状VB动脉样硬化疾病和低流状态的患者的血液动力学和临床结果.
- 评估这些内血管程序的长期疗效和安全性.
主要方法:
- 两所医院对17名患者进行了回顾性审查,这些患者接受了血管造形手术,并因表征性VB动脉样硬化病而在两个医院进行了支架.
- 量化MRA (QMRA) 用于测量造前和后的流量.
- 收集了临床结果,包括周围手术和复发性中风.
主要成果:
- 血管整形和支架显著改善了基底和后脑动脉 (PCA) 流量 (p <0.05),根据VERiTAS标准正常化.
- 四名患者 (23.5%) 经历了外围手术性中风,其中两个是轻微的和短暂的.
- 长期随访 (平均20个月) 显示持续的通透性和流量;两名患者有复发性中风.
结论:
- 血管整形和支架可以有效地和持久地改善症状VB动脉样硬化疾病和低流量状态的患者的内流动.
- 这种内血管方法可能对这种高风险的脑血管疾病的自然史产生有利影响.
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