抑郁症对不同年龄段糖尿病患者认知功能的影响
Mingjie Yin1, Xiaoyu Xu2, Hui Fang1
1Second Department of Endocrinology and Metabolism, Tangshan Gongren Hospital, Tangshan, Hebei, China.
Journal of clinical and experimental neuropsychology
|June 30, 2023
概括
抑郁症会对糖尿病患者的认知功能产生负面影响. 这种影响随着年龄的增长而恶化,凸显了综合精神和身体健康护理的需要.
科学领域:
- 神经科学是一个神经科学.
- 内分泌学 在内分泌学.
- 老年学是一门学科.
背景情况:
- 糖尿病 (DM) 是一种慢性疾病,影响全球数百万人.
- 认知障碍在老年人群中越来越令人担忧.
- 在DM患者中,抑郁症与认知功能之间的相互作用需要进一步研究.
研究的目的:
- 为了检查糖尿病患者抑郁症和认知功能之间的关系.
- 评估年龄如何影响抑郁症对DM患者认知表现的影响.
主要方法:
- 利用了来自2016年Kailuan集团员工体检的6,549名糖尿病患者的数据.
- 使用迷你精神状态检查 (MMSE) 进行认知功能评估和抑郁症自我评价抑郁量表 (SDS).
- 应用了通用线性回归模型来分析不同年龄组和风险因素SDS得分和MMSE得分之间的关联.
主要成果:
- 在较高的SDS得分 (抑郁症) 和较低的MMSE得分 (认知功能) (β = -0.06;P < 0.01) 之间发现了显著的负相关性.
- 在SDS得分和年龄组之间观察到对认知功能的相互作用效应.
- 教育水平也显示出与SDS分数的相互作用效应.
结论:
- 抑郁症对糖尿病患者认知功能的有害影响随着年龄的增长而放大.
- 这些发现强调了治疗老年DM患者抑郁症的重要性,以保持认知健康.
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