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囊泡切割与在家取样以确定尿蛋白的比较:猫的肌素比率和尿液特异重量
Femke Mortier1, Sylvie Daminet1, Luc Duchateau2
1Small Animal Department, Ghent University, Ghent, Belgium.
Journal of veterinary internal medicine
|June 30, 2023
概括
在家收集的尿样是一种可行的替代品,用于猫类尿液分析的兽医诊所囊. 然而,由于蛋白质:肌氨酸比率和尿液特异性重度的潜在差异,使用一致的方法监测猫.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 尿液分析对于诊断猫的慢性病至关重要.
- 囊细胞切割并不总是可行的尿液收集.
- 对比在家收集的空白样本与猫的临床囊切片的数据有限.
研究的目的:
- 为了比较尿蛋白:肌素比率 (UPC) 和尿液特异性重量 (USG) 在家庭收集的空白样本和临床获得的猫的囊样本之间.
- 为了确定两种采集方法之间的蛋白尿亚阶段和尿液度的临床显著差异.
主要方法:
- 这是一项前性研究,涉及92只健康和患病的客户猫.
- 业主在家里收集空白的尿样.
- 囊检测在家庭采样后1至15小时内在诊所进行.
主要成果:
- 55%的业主成功在家收集尿液样本.
- 与空白样本相比,细胞凝聚样本显示出更高的UPC (平均±SD差 = 0.09 ±0.22) 和较低的USG (平均±SD差 = -0.006 ±0.009).
- 在两种方法之间观察到蛋白尿症子阶段 (28%的猫) 和尿液缩能力 (18%的猫) 的临床相关差异.
结论:
- 在家收集的尿样代表了猫类尿液分析中囊切片的有效替代品.
- 由于UPC和USG的潜在临床相关变异,建议在个人猫监测中采用一致的尿液采集方法.
- 这一发现支持使用业主收集的样本来减少对临床内囊细胞检测的需求.
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