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对糖摄入表型及其相关物质的选择性压力:一个复制研究

Nancy K Dess¹, Clinton D Chapman¹, Paulina M Jacobi¹

¹Department of Psychology, Occidental College, Los Angeles, CA, United States.

Chemical senses

|June 30, 2023

概括

选择性繁殖创造了高和低糖摄入量的老鼠 (HiS和LoS). 复制线 (HiS-R和LoS-R) 证实了摄入量和行为差异的快速选择,尽管出现了一些变异.

科学领域:

行为遗传学行为遗传学
人类行为的动物模型.
味道和养研究研究.

背景情况:

选择性繁殖高糖和低糖 (HiS和LoS) 的老鼠揭示了各种行为差异.
这些差异反映了人类的品味,个性和精神病理学研究.
最初的生产线被终止,需要进行复制研究.

研究的目的:

测试可复制,快速选择的糖摄入表型和相关物质.
检查复制线的复制模式和分歧.
研究味道偏好的遗传和行为基础.

主要方法:

选择性繁殖复制高糖和低糖 (HiS-R和LoS-R) 的老鼠系5代.
评估各种口味剂 (撒卡林,糖,氨酸改糖,NaCl,乙醇) 和食品的摄入量.
评估非吞性行为:剥夺引起的过度活动,声学惊和开放场地行为.

主要成果:

HiS-R和LoS-R线在含糖,分糖,因改糖,NaCl和复杂食物的摄入量上有显著差异.
开放场的行为也显示出显著的线差.
一些观察到的差异与原来的HiS和LoS线不同.

结论:

对糖摄入量和相关行为进行快速选择可以在复制的老鼠系中复制.
复制和分歧的模式为养和行为的遗传结构提供了洞察力.
需要进一步的研究,以了解原始和复制线之间的观察差异的原因.

关键词:

防御性行为防御性行为消化过程中的消化行为.鼠类鼠类鼠类鼠类鼠类复制复制复制复制复制复制复制糖摄入量糖摄入量选择性繁殖是一种选择性繁殖.

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