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在孔手术和术后排水后的复发性慢性腹腔下血瘤:系统性审查和元分析
Roger Lodewijkx1,2, Merijn Foppen1,2, Kari-Anne Mariam Slot1,2
1Department of Neurosurgery, Neurosurgical Center Amsterdam, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Operative neurosurgery (Hagerstown, Md.)
|June 30, 2023
概括
经过孔手术和排水治疗的慢性体内血瘤的复发率为12.8%. 本系统性审查阐明了这种常见的神经外科手术的复发率.
科学领域:
- 神经外科 神经外科
- 临床流行病学临床流行病学
背景情况:
- 在经手术后排水的洞手术后,慢性腹腔内血瘤 (CSH) 的复发率在现有文献中有显著的差异.
- 准确了解复发率对于优化患者管理和手术结果至关重要.
研究的目的:
- 进行系统性审查和元分析,以确定使用洞穴手术和术后排水治疗的慢性体内血瘤的确切复发率.
主要方法:
- 根据PRISMA指南,对PubMed和EMBASE数据库进行了全面的搜索.
- 包含的研究的质量评估使用了纽卡斯尔-太华规模和柯克兰偏差风险工具.
- 使用随机效应模型计算了聚合发病率,使用I2统计数据评估异质性.
主要成果:
- 系统性审查包括189项研究,包括34,393名患者 (每位患者分析) 和3,078名血液瘤 (每位血液瘤分析).
- 总的综合复发发病率为11.2% (每个患者) 和11.0% (每个血液瘤).
- 在最高质量的研究 (48项研究,15298名患者) 中,综合复发发病率为12.8% (95% CI:11.4-14.2). 与治疗相关的死亡率为0.7%.
结论:
- 经过洞手术和术后排水治疗的慢性体内血瘤的整体复发率估计为12.8%.
- 与治疗相关的死亡率很低,综合发病率为0.7%.
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