身体脂肪指数与妊娠期糖尿病之间的关联:一项前性队列研究
Sawanya Benchahong1, Prasert Sunsaneevithayakul1, Dittakarn Boriboonhirunsarn1
1Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, THA.
身体脂肪指数 (BFI) 比体重指数 (BMI) 更好地预测妊娠糖尿病 (GDM). 怀孕期间BFI>0.5的孕妇患GDM的风险更高.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 代谢健康 代谢健康
- 诊断生物标志物 诊断生物标志物
背景情况:
- 体重指数 (BMI) 是一种常见但不完美的衡量标准,用于评估妊娠糖尿病 (GDM) 风险.
- 体重指数不能准确地反映身体脂肪的分布,可能低估了GDM风险.
- 身体脂肪指数 (BFI),包括内脏脂肪组织 (VAT) 和皮下脂肪组织 (SAT),显示出作为优越的GDM预测器的希望.
研究的目的:
- 为了比较孕妇BFI>0.5和BFI ≤0.5.5的孕妇之间的GDM风险.
- 评估BFI和BMI作为GDM的诊断工具.
- 为了确定在怀孕期间GDM的独立风险因素.
主要方法:
- 在怀孕14周之前通过超声波测量母亲的腹部SAT和VAT厚度.
- 使用公式计算的BFI:增值税×SAT/高度.
- 怀孕期间进行的GDM查;BFI组之间的GDM比率比较.
主要成果:
- BFI>0.5的女性年龄较大,BMI较高,更有可能超重/肥胖.
- 在BFI>0.5组中,GDM患病率明显高于BFI>0.5组 (24.4%对11.3%).
- BFI和BMI对GDM表现出类似的诊断能力 (AUCs ≈0.64).
结论:
- 一个BFI>0.5与明显增加GDM的可能性有关.
- BFI和BMI对GDM具有可比的诊断性能.
- 升高的BFI (>0.5) 和BMI (≥25 kg/m2) 是GDM的独立风险因素.
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