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Updated: Jul 25, 2025

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在人类固体瘤中研究人类NK细胞的小鼠模型

Monica Parodi1, Simonetta Astigiano2, Paolo Carrega3

  • 1Unità Operativa UO Patologia e Immunologia Sperimentale, IRCCS Ospedale Policlinico San Martino, Genova, Italy.

Frontiers in immunology
|June 30, 2023
PubMed
概括

鼠标模型对于研究自然杀手 (NK) 细胞至关重要. 先进的人性化小鼠模型,如NOG和NSG,对于在临床前研究中研究人类NK细胞行为和功能至关重要.

关键词:
人在老鼠模型中的人类人性化的小鼠.自然杀手细胞是自然杀手细胞.固体瘤是一个固体瘤.瘤免疫力 免疫力

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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