在耐火性慢性便秘患者中未被识别的功能性消化不良:对三级队列的分析
Taylor Boyd1, Mary Paz2, Imama Ahmad2
1Harvard Medical School, Boston, Massachusetts.
Gastro hep advances
|June 30, 2023
概括
几乎40%的耐火功能性便秘 (FC) 的成年人也患有功能性消化不良 (FD). 在FC患者中同时出现的FD与更多的食道问题和膨胀有关,这表明诊断和治疗的潜在重叠.
科学领域:
- 胃肠病学 胃肠病学
- 功能性肠胃疾病 功能性肠胃疾病
背景情况:
- 功能性便秘 (FC) 患者经常表达对现有治疗方法的不满.
- 在FC中持续的症状可能表明与功能性消化不良 (FD) 发生重叠.
研究的目的:
- 确定具有耐火功能性便秘 (FC) 的成年人同时出现功能性消化不良 (FD) 的患病率.
- 识别与并发性FD和FC相关的症状和表现.
主要方法:
- 对308名耐火性FC患者进行了回顾性队列研究.
- 罗马四号标准被用于识别并发的FD.
- 数据包括人口统计,症状和心理并发症.
主要成果:
- 38.6%的耐火性FC患者 (3.0 ± 2.3次治疗失败) 患有并发性FD.
- 同时的FD与食道症状 (OR=3.1) 和膨胀/膨胀 (OR=2.67) 相关.
- 同时患有FD的患者有更高的饮食障碍史率 (21.0%) 和避免/限制性食物摄入障碍症状 (31.9%).
结论:
- 在第三级队列中,近40%的耐火性FC患者也符合FD的标准.
- 同时的FC和FD与食道症状增加和膨胀相关.
- 识别并发性FD为耐火性FC患者提供了新的治疗途径.
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