皮肤电神经场刺激改善了儿童周期性吐综合征的并发症
Katja Karrento1, Liyun Zhang2, William Conley1
1Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, United States.
Frontiers in pain research (Lausanne, Switzerland)
|June 30, 2023
概括
皮肤电神经场刺激 (PENFS) 有效地减少了周期性吐综合征 (CVS) 的儿童的腹痛和焦虑. 这种非侵入性耳部治疗也改善了睡眠和生活质量,并带来了持久的焦虑益处.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 神经科学是一个神经科学.
- 医疗器械 医疗器械
背景情况:
- 在儿童中,循环吐综合征 (CVS) 会导致严重的腹痛和并发症,严重影响他们的生活质量.
- 肠-大脑相互作用的障碍在儿科CVS中很常见.
- 耳膜穿皮电神经场刺激 (PENFS) 是在这些情况下治疗腹痛的非侵入性选择.
研究的目的:
- 评估PENFS在治疗儿科CVS患者腹痛方面的疗效.
- 评估PENFS对与CVS相关的常见并发症的影响.
- 确定PENFS对患有CVS的儿童整体生活质量的影响.
主要方法:
- 一项前性,开放性研究,涉及30名患有耐药性心血管系统的儿童 (8-18岁).
- 连续6周进行耳部PENFS治疗.
- 使用经过验证的疼痛 (API),焦虑 (STAI-C),睡眠 (PSQI) 和生活质量 (PROMIS Pediatric Profile-37) 的问卷进行评估,在基线,6周和4-6个月的随访.
主要成果:
- 在6周和延长后续 (p<0.003) 观察到腹痛指数 (API) 得分显著降低.
- 在6周和延长随访期间,国家焦虑得分显著下降 (p<0.0001).
- 报告指出,睡眠和生活质量 (身体功能,焦虑,疲劳,疼痛干扰) 短期有所改善,而长期的焦虑有所改善.
结论:
- 这项研究是首次证明PENFS对儿科CVS疼痛和并发症的疗效.
- 耳部PENFS提供了一个有前途的非侵入性治疗选择,用于儿科CVS.
- PENFS对焦虑,睡眠和生活质量有显著的益处,对焦虑有持续的影响.
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