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通过口腔内镜肌切除术对于患有秋症的儿科患者是安全有效的:长期随访研究
Ya-Wei Bi1, Xiao Lei2, Nan Ru1
1Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
World journal of gastroenterology
|June 30, 2023
概括
通过口腔内镜肌切除术 (POEM) 是对儿科阿喀拉西亚的一种安全有效的治疗方法,显示出显著的症状缓解和改善生活质量 (QoL). 儿童的长期疗效与成年人相同,并发症率相似.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
- 儿科手术 儿科手术
背景情况:
- 通过口腔内镜肌切除术 (POEM) 是对儿科的新兴治疗方法.
- 有限的数据存在于POEM的长期疗效在儿童和青少年与秋症.
研究的目的:
- 评估POEM在儿科阿喀拉西亚患者的安全性和长期疗效.
- 将儿科患者的POEM结果与成人患者的POEM结果进行比较.
主要方法:
- 回顾性队列研究比较了接受POEM的儿科 (18岁以下) 和成人 (18-65岁) 秋拉西亚患者.
- 1:1对长期结果的后续分析进行匹配.
- 评估程序参数,不良事件,临床成功,GERD和生活质量 (QoL).
主要成果:
- 在48名儿科和1025名成年患者中进行了POEM.
- 儿科和成人组之间的POEM并发症率没有显著差异 (14.6%对14.6%).
- 在中位数5.7年的随访后,儿科患者的临床成功率高 (97.2%);与成年人相比,在POEM后的GERD发病率中没有显著差异. 在这两组中,QOL都有显著的改善.
结论:
- 诗歌是一种安全有效的治疗儿科阿喀拉西亚.
- 达到显著的症状缓解和改善儿科患者的生活质量.
- 儿童的长期结果与成年人相似.
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