小肠细菌过度生长的流行病学
Irina Efremova1, Roman Maslennikov1,2, Elena Poluektova1,3
1Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow 119435, Russia.
World journal of gastroenterology
|June 30, 2023
概括
小肠细菌过度生长 (SIBO) 影响了超过三分之一的消化系统问题患者,并与许多健康状况有关. 需要进一步研究根除SIBO以改善患者的治疗结果.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 微生物学 微生物学
背景情况:
- 小肠细菌过度生长 (SIBO) 涉及小肠中过度存在的细菌.
- 通过呼吸检测,SIBO在33.8%的胃肠道症状患者中被诊断出来.
- 危险因素包括吸烟,使用质子抑制剂和年龄的增加.
研究的目的:
- 定义小肠道细菌过度生长 (SIBO) 和其流行情况.
- 确定与SIBO相关的条件和风险因素.
- 探索SIBO.的病原遗传意义和临床影响.
主要方法:
- 在患有胃肠道疾病的患者中检测SIBO的呼吸测试.
- 分析SIBO与各种人口,临床和疾病因素之间的关联.
- 对SIBO病原和相关条件的现有文献的综述.
主要成果:
- SIBO与吸烟,胀气,腹痛,贫血和功能性胃肠道疾病有显著的相关性.
- 一系列系统性疾病,包括肝病,糖尿病和自身免疫性疾病,都与SIBO有关.
- 由于自主神经病变或门外高血压等因素,耳腔过渡时间减慢,有助于SIBO的发展.
- 肝硬化和糖尿病等疾病的疾病严重程度与SIBO存在相关.
结论:
- SIBO是一种常见的疾病,与许多胃肠道和全身疾病有关.
- 了解SIBO在疾病发病过程中的作用对于患者管理至关重要.
- 进一步调查SIBO根除对疾病预后的影响是有必要的.
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