乳房DWI分析在加多利尼姆对比剂施用前和之后 - - 在1.5T和3.0T上进行内科分析
Kay J J van der Hoogt1, Robert-Jan Schipper, Ronni Wessels
1From the Department of Radiology, The Netherlands Cancer Institute, Amsterdam, the Netherlands (K.J.J.H., R.-J.S., R.W., R.G.H.B., R.M.M.); GROW School of Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands (K.J.J.H., R.G.H.B.); Department of Surgery, Catharina Hospital Eindhoven, Eindhoven, the Netherlands (R.-J.S.); Department of Medical Physics, the Netherlands Cancer Institute, Amsterdam, the Netherlands (L.C.B.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (R.M.M.); and Danish Colorectal Cancer Unit South, Vejle University Hospital, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark (R.G.H.B.).
在多参数MRI中进行后对比扩散权重成像 (DWI) 并不会显著改变病变的分类. 这种缩短的MRI协议集成了DWI,而不会增加扫描时间,提高乳腺损伤评估的效率.
科学领域:
- 放射学 放射学是一门学科.
- 医疗成像医学成像
- 在瘤学瘤学.
背景情况:
- 扩散加权成像 (DWI) 越来越多地用于动态对比增强乳房MRI.
- 将DWI集成到标准协议中可以增加扫描时间.
- 获得DWI后对比可以提供多参数MRI而不需要扩展扫描.
研究的目的:
- 评估后对比DWI是否会在统计学上影响缩短的MRI协议中的病变分类.
- 评估对比后DWI对乳房外膜的影响.
- 确定将DWI纳入对比增强阶段的可行性.
主要方法:
- 查或手术前MRI的回顾性分析 (1.5 T/3 T).
- DWI获得了gadolinium前和后的对比度 (gadoterate大光).
- 使用威尔科克森签名等级测试比较的明显扩散系数 (ADCs);与加权卡帕比较的扩散度水平.
主要成果:
- 对纤维腺组织或损伤的平均ADC没有显著变化.
- 在18%的病变中观察到扩散水平的变化 (加权 κ = 0.75).
- 没有观察到对损伤分类或瘤的显著影响.
结论:
- 对于缩短的多参数MRI协议,支持DWI获取2分钟后对比.
- 使用b150-b800的ADC计算与gadoterate明是可靠的对比后.
- 这种方法可以实现多参数MRI,而无需额外的扫描时间.
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