CA125在预测急性复杂结肠分泌体炎的价值
Yaniv Zager1,2, Saed Khalilieh1,2,3, Aiham Mansour1,2
1Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
International journal of colorectal disease
|June 30, 2023
概括
血清CA125水平可以准确地预测复杂的膜炎. 患有急性角膜炎的患者的CA125水平较高表明疾病严重程度增加,需要进行干预.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 临床诊断 临床诊断 临床诊断
背景情况:
- CA125是卵巢癌的血清标志物,但在腹刺激时,水平可能会升高.
- 急性膜炎是一种常见的疾病,严重程度各不相同.
研究的目的:
- 调查血清CA125水平是否可以预测急性分炎患者的疾病严重程度.
主要方法:
- 对151名计算机断层扫描证明的急性左侧结肠分泌体炎患者进行前性观察性研究.
- 在呈现时分析了血清CA125水平.
- 统计分析包括单变量,多变量和ROC分析,以将CA125与复杂的分炎,干预需要,LOS和再入院等结果相关联.
主要成果:
- 复杂分泌体炎 (中位数16U/ml) 与无并发症 (中位数8U/ml) 的CA125水平显著更高.
- CA125与Hinchey严重程度等级和腹大小相关.
- ROC分析显示,CA125在曲线下面的面积 (0.82) 对于预测复杂的分泌体炎比白细胞计数,体温或中性粒细胞-淋巴细胞比率更高.
- CA125是复杂分炎 (OR 1.12) 的唯一独立预测因子.
结论:
- CA125可以准确地区分简单和复杂的分泌体炎.
- 需要进一步的前性研究来证实这些发现.
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