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手术前的手指测量数据可以预测口腔内镜肌肉切除术后的症状改善,用于治疗
Joshua Lyons1,2, Christina Boutros3,4, Saher-Zahra Khan3,4
1Department of Surgery, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Lakeside 7, Cleveland, OH, 44106, USA. Joshua.Lyons@UHHospitals.org.
Surgical endoscopy
|June 30, 2023
概括
在阿喀拉西亚患者中,高集成放松压力 (IRP) 预测在口服内镜肌切除术 (POEM) 后,与其他治疗不同,更好地缓解症状. 阿哈拉西亚类型没有预测POEM结果.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 食道运动障碍 食道运动障碍
背景情况:
- 通过口腔内镜肌切除术 (POEM) 是有效的阿喀拉西亚,但预测反应是具有挑战性的.
- 从历史上看,高低食道关节压力预测了其他内镜治疗的不良结果.
- 这项研究调查了手术前的力度测量是否可以预测POEM的成功.
研究的目的:
- 评估手术前的高分辨率测量数据是否可以预测POEM后治疗治疗的反应.
- 为了确定秋拉西亚类型和综合放松压力 (IRP) 是否与需要进一步干预或症状改善相关.
主要方法:
- 144名接受POEM (2014-2022) 的患者的回顾性分析.
- 采集了手术前的高分辨率计量和埃卡德特症状得分.
- 使用单变量分析评估了与术后结果的阿喀拉西亚类型和IRP的相关性.
主要成果:
- 阿哈拉西亚类型没有预测需要进一步干预或减轻症状.
- 较高的IRP并没有预测需要进一步干预.
- 较高的IRP与术后埃卡德得分 (p=0.03) 的较大降低有关.
结论:
- 阿哈拉西亚类型不是POEM结果的预测因素.
- 虽然IRP并不预测需要重新干预,但更高的IRP与POEM后改善的症状缓解有关.
- 具有较高IRP的患者可能从POEM中显著受益,与其他内镜治疗的发现相反.
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