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Updated: Jul 25, 2025

Laser Capture Microdissection of Glioma Subregions for Spatial and Molecular Characterization of Intratumoral Heterogeneity, Oncostreams, and Invasion
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NUDT21通过对LAMC1的差异替代多基基化改变质瘤迁移

Venkata Soumith Jonnakuti1,2,3,4, Ping Ji5, Yipeng Gao3

  • 1Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, USA.

Journal of neuro-oncology
|June 30, 2023
PubMed
概括

NUDT21通过控制LAMC1的替代多基解 (APA) 来调节质瘤细胞的行为. 缩短LAMC1的3'非翻译区域 (UTR) 会增强其表达,促进质瘤细胞迁移并预测不良预后.

关键词:
变性聚亚脱化 (Alterative Polyadenylation) 是一种可以改变多亚脱化的方法.一个LAMC1一个LAMC1NUDT2121 裸体的时间这是一种PolyA矿物.

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