跨诊断过程将创伤后应激障碍症状与酒精使用严重程度联系起来
Kate Wolitzky-Taylor1, Tanya Smit2, Anka A Vujanovic2,3
1Integrated Substance Abuse Programs, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California - Los Angeles, Los Angeles, California, USA.
Journal of dual diagnosis
|June 30, 2023
概括
焦虑敏感性,而不是情绪调节,显著介导创伤后应激障碍 (PTSD) 和酒精使用障碍 (AUD) 之间的联系. 这一发现可能会为同时发生的PTSD和AUD提供有针对性的干预措施.
科学领域:
- 精神病学和行为科学 精神病学和行为科学
- 临床心理学 临床心理学
- 成 药物 药物 药物 药物
背景情况:
- 在创伤后应激障碍 (PTSD) 和酒精使用障碍 (AUD) 之间存在很高的并发症.
- 了解跨诊断构造对于解释这种并发症和开发有效治疗至关重要.
- 现有的研究需要探索关联PTSD和AUD的潜在机制.
研究的目的:
- 检查焦虑敏感性和情绪调节困难是否调解PTSD症状严重程度和酒精使用严重程度之间的关联.
- 调查应对饮酒动机是否能缓和这种间接影响.
- 确定导致PTSD-AUD并发症的跨诊断因素.
主要方法:
- 使用了一个大型的,横截面数据集 (N=513) 与国家招聘.
- 评估了PTSD症状严重程度 (PCL-5),酒精使用严重程度 (AUDIT),焦虑敏感度 (SSASI) 和情绪调节困难 (DERS-16).
- 雇佣调解和适度分析,包括共同变量,如出生时分配的性别.
主要成果:
- 焦虑敏感度 (SSASI) 显著调解了PTSD症状严重程度和酒精使用严重程度之间的关系.
- 情绪调节困难 (DERS-16) 在单独的模型中显示出显著的间接影响,但在与SSASI.SI同时分析时没有显著的间接影响.
- 应对饮酒动机并没有缓解间接影响.
结论:
- 焦虑敏感性成为PTSD-AUD并发症的关键跨诊断过程.
- 虽然情绪调节困难可能起到作用,但焦虑敏感性显示出更强有力的证据,作为调解者.
- 这些研究结果支持开发针对焦虑敏感性的干预措施,以应对同时发生的PTSD和酒精使用.
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