艾加维德基拉纳果实相对Psyllium植物对功能性便秘:随机双盲临床试验
Enrique Coss-Adame1, Maria F García-Cedillo1, Gustavo Bustillo-Armendáriz2
1Departments of Gastroenterology.
Journal of clinical gastroenterology
|June 30, 2023
概括
阿加夫果实素 (AF) 有效地治疗功能性便秘,表现出与类植物相似的结果. 这项研究证实了AF作为改善肠道规律性和症状的可行治疗选择.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 纤维补充剂是便秘的主要治疗方法.
- 果实素,包括来自甲的果实素,具有有益于肠道健康的益生菌性质.
研究的目的:
- 评估Agave tequilana Weber蓝色品种果实素 (Predilife) 在缓解功能性便秘症状方面的有效性.
- 为了比较青叶果实素 (AF) 与 (PP) 作为治疗便秘的方法.
主要方法:
- 一项随机双盲研究涉及79名功能性便秘患者.
- 参与者接受了果果糖 (5g或10g) 或,有或没有马尔托德,为期8周.
- 治疗的有效性是通过完整的自发性肠道排便,便的一致性和生活质量来衡量.
主要成果:
- 所有治疗组都显示了肠道排便,便一致性和生活质量的显著改善.
- 阿加夫果实素,特别是在5g与马尔托德克斯特林一起,显示出自发性肠道排便的显著增加.
- 在 agave fructans 和 psyllium 之间没有观察到响应率或不良事件的显著差异.
结论:
- 果果糖 (Predilife) 在治疗功能性便秘方面与一样有效.
- 在不同剂量和与马尔托德克斯特林结合使用时,AF显示出有效性.
- 阿加夫果实素代表了一种可行的和有效的治疗选择,用于管理功能性便秘.
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