绝经时的年龄与2型糖尿病患者的微血管并发症无关
Shuyao Sun1,2, Rong Du1,2, Suyuan Wang1,2
1Department of Endocrinology and Metabolism, Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region, Sichuan, China.
Medicine
|June 30, 2023
概括
早期更年期在2型糖尿病女性中没有显示与微血管并发症的关联. 这项研究发现绝经时的年龄与糖尿病视网膜病变,脏疾病或神经病变之间没有联系.
科学领域:
- 内分泌学 在内分泌学.
- 糖尿病学 糖尿病学
- 妇女健康 妇女健康
背景情况:
- 更年期是女性生活中重要的生理事件.
- 2型糖尿病是一种常见的慢性疾病,已知有微血管并发症.
- 更年期年龄对糖尿病并发症的潜在影响需要进一步调查.
研究的目的:
- 为了研究更年期 (AM) 时的年龄与患有2型糖尿病的更年期后妇女中微血管并发症的存在之间的关联.
主要方法:
- 一项涉及298名患有2型糖尿病的绝经后妇女的横截面研究.
- 参与者根据更年期的年龄分为三组 (<45,45-49岁和≥50岁).
- 使用后勤回归分析来评估AM和糖尿病微血管并发症 (视网膜病变,病变,神经病变) 之间的关系,并调整了混因素.
主要成果:
- 在更年期组的不同年龄段,糖尿病视网膜病变,慢性病或糖尿病外围神经病变的患病率没有发现统计学意义上的差异.
- 经过调整的分析证实更年期时的年龄与糖尿病视网膜病变 (P = .511),慢性病 (P = .280) 或糖尿病外围神经病变 (P = .853) 的存在之间没有相关性.
结论:
- 早期更年期 (年龄<45岁) 与2型糖尿病女性微血管并发症风险增加无关.
- 进一步的前性研究是有必要的,以明确阐明绝经时的年龄和糖尿病微血管并发症之间的关系.
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