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Updated: Jul 25, 2025

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
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新的4-(N-cinnamoylbutyl) 氨基亚克里丁作为潜在的多阶段抗等离子体诱导剂

Mélanie Fonte1, Diana Fontinha2, Diana Moita2

  • 1LAQV-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Portugal.

European journal of medicinal chemistry
|June 30, 2023
PubMed
概括

新的4-氨基亚克里丁衍生物显示出强大的抗疟疾活性,对抗虫寄生虫. 这些化合物对肝脏和血液阶段以及性细胞有效,没有观察到毒性.

关键词:
亚克里迪因 (Acridine) 是一种亚克里迪因.这是一种抗疟疾药.血液阶段 - 血液阶段锡南酸是一种酸.游戏细胞的游戏细胞.混合动力是一个混合动力.肝脏阶段 - 肝脏阶段多个目标的多重目标.

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