产前暴露于感知压力,孕产妇喘和胎盘大小
Andrew Williams1, Sadia Saizy1, Pauline Mendola2
1Public Health Program, Department of Population Health, School of Medicine and Health Sciences, University of North Dakota, 1301 N Columbia Rd, Grand Forks, ND, 58202, USA.
怀孕期间感知较高的压力与更小的胎盘尺寸有关,特别是体重和长度. 这种关联在患有喘和没有喘的妇女之间有所不同,突出显示了压力对胎儿发育的影响.
科学领域:
- 生殖健康 生殖健康
- 围产儿医学 围产儿医学
- 心理神经免疫学 心理神经免疫学
背景情况:
- 产前压力与不良妊娠结果有关.
- 怀孕期间的喘可能会增加压力易感性并影响结果.
- 关于母亲的压力与胎盘大小之间的关系的数据有限.
研究的目的:
- 研究孕妇感知压力与胎盘大小之间的关联.
- 探索是否喘状态改变了压力-胎盘大小关系.
主要方法:
- 使用了B-WELL-Mom队列,其中包括345名女性 (262名喘患者).
- 从病理学报告中评估胎盘体重,长度,宽度和厚度.
- 使用感知压力尺度 (PSS) 测量感知压力,跨越三个月,分为四分位数.
- 采用统计分析的概括估计方程,对共变量进行调整,并按喘状态分层.
主要成果:
- 更高的感知压力 (四分位数与1) 与明显较小的胎盘重量和长度相关.
- 在高压力和胎盘宽度或厚度之间没有发现显著的关联.
- 喘状况影响了压力与胎盘大小的联系:喘妇女的胎盘长度较短,非喘妇女的胎盘厚度较小.
结论:
- 怀孕期间感知压力的增加与胎盘尺寸的减少有关.
- 压力对胎盘发育的影响可能因喘状况而异.
- 需要进一步的研究来阐明连接压力和胎盘生长的机制.
更多相关视频
04:20Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model
Published on: July 12, 2024
05:31Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
相关概念视频
Asthma-I: Introduction
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Asthma-III: Symptoms and Complications
Classification of Asthma
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
