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在Lactobacillus johnsonii基因组中存在宿主特异性的证据,以及其对家禽中的益生菌潜力的影响

Abigail Johnson¹, Elizabeth A Miller¹, Bonnie Weber¹

¹Department of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, MN, USA.

Poultry science

|June 30, 2023

概括

宿主特定的益生菌菌株,如Lactobacillus johnsonii,对于家禽的健康至关重要. 将益生菌适应它们的动物宿主显著提高了它们的殖民和性能,改善了鸟类的健康和生产结果.

科学领域:

微生物学和动物科学
益生菌和肠道健康
禽类生产和畜牧业的动物养殖

背景情况:

对于生产动物来说,益生菌菌株的选择传统上侧重于表型特征.
新出现的证据表明,与其动物宿主共同进化的宿主特异性菌株提供了卓越的殖民性和有效性.
在提高商业家禽的表现方面,Lactobacillus johnsonii已经显示出有前途.

研究的目的:

调查宿主适应对禽类中Lactobacillus johnsonii益生菌潜力的影响.
为了确定共进化的遗传信号是否与宿主特异性和益生菌有效性相关.
为了评估宿主特异性与非特异性L. johnsonii菌株在家禽中的表现.

主要方法:

对自然分离的204种来自和火的L. johnsonii菌株进行了基因分析.
在体外表型选中,针对所需的益生菌特征对分离物进行异型选.
使用精选的L. johnsonii菌株,对商业火和肉进行性能试验.

主要成果:

在L. johnsonii分离物中观察到与宿主动物共同进化的强烈的系遗传信号.
具有强大的体外表型的宿主特异性L. johnsonii菌株在火幼中提高了早期生活性能.
特定于的L. johnsonii菌株在肉中表现出优异的整体性能,与非特定菌株相比.

结论:

宿主适应显著影响细菌菌株的益生菌潜力,如L. johnsonii.
在益生菌菌株选择中采用宿主特定的方法可以提高家禽的疗效.
这种自上而下的策略为选和识别有前途的益生菌候选人提供了有效的方法.

关键词:

brojler 肉肉是一个宿主适应宿主适应乳酸细菌菌 (lactobacilli) 是一种乳酸细菌.益生菌益生菌是一种益生菌.土耳其土耳其土耳其

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