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Updated: Jul 25, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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微调GPCR介导的神经调节,通过通过不同的G蛋白子单元偏向信号传递

Jong-Chan Park1, Alex Luebbers1, Maria Dao2

  • 1Department of Biochemistry & Cell Biology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.

Molecular cell
|June 30, 2023
PubMed
概括

神经元蛋白GINIP通过偏好Gβγ而不是Gα子单元来调节抑制性G蛋白合受体 (GPCR) 信号传递. 这种机制可以防止神经传递失衡,并降低小鼠的发作易感性.

关键词:
这是一种G蛋白质蛋白质,G蛋白质蛋白质.在GPCR中,GPCR是指GPCR.这是一个GTPase.在KIAA104545中使用.PHF24 PHF24 PHF24 PHF24 PHF24 PHF24 PHF24 PHF24 PH神经元神经元的神经元它们是神经递质神经递质.发作 发作 这些

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