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Updated: Jul 25, 2025

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides
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Published on: July 26, 2018

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瓜诺辛基的可逆ADP-ribosylation的分子基础

Marion Schuller1, Roberto Raggiaschi1, Petra Mikolcevic2

  • 1Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

Molecular cell
|June 30, 2023
PubMed
概括

研究人员发现了一种新的细菌毒素-抗毒素系统,DarT1-NADAR,可逆地修改DNA中的瓜诺辛基. 这一发现揭示了细菌和真核生物中氨酸修饰的保存机制.

关键词:
在ADP-ribosylation过程中.它们是ADP-ribosyl转移酶.造成的DNA损伤是DNA损伤.基因组的修改 基因的修改 基因的修改在PARP中,PARP是PARP.毒素-抗毒素系统的毒素.

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