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Updated: Jul 25, 2025

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I组mGluRs阳性全调节剂在Poly I:C大鼠模型中改善了与精神分裂症相关的行为和分子缺陷

Sacide Yildiz Taskiran1, Mehmet Taskiran2, Gokhan Unal3

  • 1Department of Physiology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye.

Pharmacology, biochemistry, and behavior
|June 30, 2023
PubMed
概括

孕产妇接触到的多氨酸-多乙酸 (Poly I:C) 会引起类似精神分裂症的症状. 积极的全调节剂 (PAMs) 向甲基酸盐受体 (mGluRs) 改善了后代的行为和减少了炎症,这表明精神分裂症的潜在治疗策略.

关键词:
诺巴姆是一种诺巴姆.JNJ 1625968585 这是一个很大的问题.聚I:C:C 是一个复合材料.RO 67-7476 的时间.精神分裂症是一种精神分裂症.这就是VU-29.

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Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
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