用于评估主动脉解剖中生活质量的患者报告结果措施:使用COSMIN方法论进行系统范围审查
Lydia Hanna1, Rama Jha2, Viknesh Sounderajah3
1Department of Surgery and Cancer, Imperial College London, London, UK; Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK.
概括
这次审查发现了许多不同的患者报告的结果指标 (PROMs),用于大动脉剖析 (AD) 生活质量 (QOL) 评估. 需要一个经过验证的,针对AD的PROM来改善QOL评估.
科学领域:
- 心血管医学 心血管医学
- 健康 结果 研究 研究 结果
- 心理测量 心理测量 心理测量
背景情况:
- 大动脉剖析 (AD) 显著影响患者的生活质量 (QOL).
- 在AD患者中评估QOL需要可靠的患者报告结果措施 (PROMs).
- 目前用于AD的PROM缺乏根据既定指南进行全面验证.
研究的目的:
- 系统地识别用于AD的QOL评估的所有PROM.
- 使用基于共识的健康测量仪器选择标准 (COSMIN) 准则来评估这些PROM的心理测量特性.
主要方法:
- 使用多个数据库 (Embase,MEDLINE,PsycINFO,CINAHL,Cochrane图书馆) 进行了全面的范围审查.
- 包括1994年至2021年期间发表的涉及AD患者和PROM患者的研究.
- 数据合成和心理特征分析遵循COSMIN的指导方针.
主要成果:
- 45项研究包括5874名患者,使用39种不同的PROM,其中SF-36是最常见的.
- 只有六项研究评估了PROM的心理测量特性,其验证有限.
- 没有一项研究报告了内容有效性,也没有一项研究完全评估了根据COSMIN标准的所有属性.
结论:
- 在阿尔茨海默病患者的QOL中使用的PROM中存在显著的异质性.
- 开发和验证专门用于大动脉剖析的PROM非常需要.
- 这将有助于在这个患者群体中对QOL进行准确和一致的评估.
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