针对急性损伤的对比增强超声波:系统性审查和元分析
Yini Li1, Lingzhi Chen1, Lu Feng1
1Southwest Medical University, Luzhou, Sichuan Province, China.
Ultrasound in medicine & biology
|June 30, 2023
概括
与对比度增强的超声波 (CEUS) 可以在血清肌素水平上升之前检测急性损伤 (AKI) 患者的微 perfusion 的变化. 这种成像技术在AKI患者的皮质中显示出减少的输液和延长的过渡时间.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 医疗成像医学成像
- 诊断技术 诊断技术
背景情况:
- 急性损伤 (AKI) 是一种严重的疾病,具有显著的发病率和死亡率.
- 早期发现AKI对于及时干预和改善患者结果至关重要.
- 目前对AKI的诊断方法,主要是基于血清肌素,在早期检测方面存在局限性.
研究的目的:
- 提供基于证据的对比增强超声波 (CEUS) 评估,用于诊断急性损伤 (AKI).
- 在高风险患者中使用CEUS定量参数评估微输液的变化.
- 确定CEUS是否能够识别血清肌素变化之前的微循环变化.
主要方法:
- 按照PRISMA指南进行了系统审查和元分析.
- 搜索了Embase,MEDLINE,Web of Science和科克兰图书馆数据库 (2000-2022年) 的数据库.
- 包括6项前性研究 (374名患者),评估使用CEUS在AKI中的皮皮质微循环.
主要成果:
- 与对照组相比,CEUS在AKI患者中显示出较低的最大强度和洗率.
- 患有AKI的患者表现出更高的平均过渡时间和达到峰值的时间.
- 这些由CEUS衍生的微 perfusion 变化是在血清肌素水平显著变化之前观察到的.
结论:
- 患有AKI的患者表现出小循环输液减少和皮质输液时间延长.
- CEUS可以量化测量这些微循环变化,表明其作为AKI早期诊断工具的潜力.
- CEUS提供了一种有前途的非侵入性方法,用于早期检测和评估AKI脏微输液异常.
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