减肥干预作为通往心脏移植的桥梁的有效性
Theo Sher1, Madison Noom1, Abdul-Rahman Diab1
1Department of Surgery, University of South Florida, Tampa, Florida.
概括
减肥干预可以显著降低等待移植的心力衰竭患者的体重和BMI. 这种方法可以通过解决肥胖症来提高心脏移植的资格.
科学领域:
- 心脏病学 心脏病学
- 减肥医学 减肥医学
- 移植医学 移植医学
背景情况:
- 许多心力衰竭 (HF) 患者由于高体重指数 (BMI) 而无法接受心脏移植.
- 减肥干预提供了减肥的潜在途径,改善了移植资格.
研究的目的:
- 对等待心脏移植的肥胖HF患者进行减肥干预的安全性和有效性进行评估.
- 为了比较手术和非手术减肥干预之间的结果.
主要方法:
- 在18名HF患者的混合后期/前性研究中,BMI>35 kg/m2.
- 通过减肥手术对非手术干预和先进的HF治疗进行分类的患者.
- 体重,BMI和左心室喷射率 (LVEF) 在干预前和干预后6个月评估.
主要成果:
- 与非手术方法 (1.9 公斤,0.7 公斤/m2) 相比,腹部手术导致显著的体重减轻 (18.6 公斤) 和BMI 降低 (6.4 公斤/m2).
- 手术患者显示LVEF改善的趋势 (+5.9%),而非手术患者显示LVEF下降的趋势 (-5.9%).
- 没有患者被丢失到随访,表明良好的耐受性.
结论:
- 减肥干预是一种安全有效的策略,用于减轻患有高血压的肥胖患者的体重和BMI.
- 这些发现支持减肥干预作为改善心脏移植候选人的可行选择.
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