相关实验视频

Updated: Jul 24, 2025

A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells
10:07

A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells

Published on: August 25, 2017

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为了无约束地纠正致癌的KRAS变体,CRISPR主要编辑

Gayoung Jang1,2, Jiyeon Kweon1, Yongsub Kim3,4

  • 1Department of Cell and Genetic Engineering, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Communications biology
|June 30, 2023
PubMed
概括

科学家们开发了通用原始编辑指导RNA (pegRNAs) 来纠正常见的KRAS瘤基因突变. 这种方法显示出作为各种KRAS驱动癌症的多功能治疗策略的希望.

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Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

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