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儿科肠道移植的管理和结果
Kera McNelis1,2, Michael E Rogers1,2, Samuel Kocoshis1,2
1Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
NeoReviews
|June 30, 2023
概括
肠道衰竭,营养吸收的损失,往往需要在儿童中进行肠道营养. 肠道移植是严重病例的拯救生命的选择,尽管需要终身免疫抑制和潜在的并发症.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 移植手术 移植手术
- 免疫学 免疫学 免疫学
背景情况:
- 肠道衰竭显著损害了营养吸收,需要支持性治疗.
- 腹腔营养是儿科肠道衰竭的主要治疗方法.
- 肠子移植是危及生命的并发症的关键干预措施.
研究的目的:
- 审查肠道移植在患有肠道衰竭的儿童中的作用和结果.
- 突出移植前和移植后护理所需的多学科方法.
- 讨论儿科肠道移植的挑战和进展.
主要方法:
- 对儿科肠道移植当前文献和临床实践的综述.
- 对结果,并发症和管理策略的分析.
- 强调对潜在移植候选人的评估和康复过程.
主要成果:
- 近年来,肠道移植的结果有所改善.
- 关键的并发症包括急性细胞排斥,移植与宿主疾病,感染和PTLD.
- 移植后需要终身免疫抑制和密集的医疗管理.
结论:
- 肠道移植是可行的,为精选的肠道衰竭儿童提供拯救生命的选择.
- 多学科的护理和广泛的评估对于成功的移植至关重要.
- 目前正在进行的研究和管理策略继续改善长期结果.
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