高强度间歇训练在COVID-19后对心脏结构和功能的影响:一个调查员盲目的随机对照试验
Iben Elmerdahl Rasmussen1, Mathilde Løk2, Cody Garett Durrer1
1Centre for Physical Activity Research, University Hospital Copenhagen, Rigshospitalet, Copenhagen, Denmark.
高强度间歇训练 (HIIT) 在从COVID-19中恢复过来的患者中有效增加了左心室质量. 这种运动干预措施表明,在因病毒住院治疗后,改善心脏健康是有前途的.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 传染病研究 传染病研究
背景情况:
- 持续的心肺健康减弱是COVID-19后常见的住院治疗.
- 由于COVID-19的心脏影响可能可以通过像HIIT这样的有针对性的炼干预来逆转.
研究的目的:
- 调查高强度间歇训练 (HIIT) 是否会增加COVID-19幸存者的左心室质量 (LVM).
- 评估HIIT在COVID-19后对功能状态和与健康相关的生活质量 (HRQoL) 的影响.
主要方法:
- 研究人员盲目的随机对照试验将12周的监督HIIT与标准护理进行比较.
- 主要结局:通过心脏MRI评估的LVM. 二次结果:肺扩散能力 (DLCO),功能状态 (PCFS) 和HRQoL (KBILD).
主要成果:
- 与标准护理相比,HIIT显著增加了LVM (平均差异6.8g,P=0.029).
- 在DLCO或其他肺功能指标中没有观察到群体之间的显著差异.
- 功能状态在HIIT组表现出描述性的改善;HRQoL在两组都有类似的改善.
结论:
- 监督高强度间歇训练 (HIIT) 是一种有效的干预措施,用于增加因COVID-19住院患者的左心室质量.
- 特别针对HIIT的目标是改善心脏,而肺功能在干预组和对照组都逐渐恢复.
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