怀孕期间抗M抗体的管理:一个病例报告
Emily R Leibovitch1, Robert T Carlisle2
1John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii.
Family practice
|July 1, 2023
概括
抗M抗体虽然能够引起胎儿和新生儿的血液溶解性疾病 (HDFN),但可能不需要在怀孕期间进行密集监测. 一个案例审查表明,一种不那么密集的方法可以有效地管理抗M抗体.
科学领域:
- 免疫学 免疫学 免疫学
- 产科 产科 产科 产科 产科
- 周围生理学 周围生理学
背景情况:
- 抗M抗体是天然存在的,可以构成胎儿和新生儿 (HDFN) 溶血性疾病的风险.
- HDFN可能导致严重的胎儿并发症,包括贫血,胎儿水解,缺氧,心力衰竭和胎儿死亡.
- 抗M抗体与少量报告的高强度肺炎病例有关.
研究的目的:
- 审查当前关于怀孕期间管理抗M抗体的指导方针.
- 建议在怀孕期间对抗M抗体进行不那么密集的管理策略,并以病例报告为依据.
主要方法:
- 这里介绍了一个怀孕个体的病例报告,该个体有阳性抗M血的病史.
- 这位患者之前有过一个健康的婴儿,尽管有抗M抗体.
- 管理决策的依据是文献审查和特定抗体的特征.
主要成果:
- 患者的抗M抗体水平较低导致决定不进行密集的母婴监测.
- 患者在38周怀孕时分娩了一个健康的婴儿,没有并发症.
- 这一结果支持一种更细微的管理方法.
结论:
- 抗红细胞 (RBC) 抗体,如抗M,通常在怀孕查期间检测到.
- 虽然经常建议进行密集监测,但了解特定抗体可以进行量身定制的,不那么密集的护理.
- 医生熟悉指南和特定抗体有助于患者咨询,遵守,并减少不必要的医疗干预.
更多相关视频
05:45Human Serum Anti-aquaporin-4 Immunoglobulin G Detection by Cell-based Assay
Published on: April 5, 2019
23.4K
05:36Author Spotlight: Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination
Published on: July 7, 2023
8.3K
相关概念视频
Development of Immunocompetence
363
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
363
Transcytosis of IgG
2.8K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
2.8K
Rh Blood Group
1.6K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.6K
Mitral Valve Prolapse III: Nursing Management
17
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
17
